| 发明名称 |
HIGH LEVEL EXPRESSION OF FUNCTIONAL HUMAN PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) IN (E. COLI) |
| 摘要 |
Biologically functional mature E. coli-expressed recombinant PAI-1 is disclosed, as well as plasmid expression vectors for production of rPAI-1, and a method for identifying inhibitors of the binding of PAI-1 and t-PA. |
| 申请公布号 |
AU5649390(A) |
申请公布日期 |
1990.11.29 |
| 申请号 |
AU19900056493 |
申请日期 |
1990.05.08 |
| 申请人 |
E. I. DU PONT DE NEMOURS AND COMPANY |
发明人 |
ROBERT MADARA KNABB;THOMAS MICHAEL REILLY;GARY LEE DAVIS;WILLIAM PERRY SISK |
| 分类号 |
A61K38/55;A61K38/00;A61P7/04;C07K14/435;C07K14/705;C07K14/81;C12N1/21;C12N15/09;C12P21/02;C12R1/19;G01N33/53;G01N33/573;G01N33/577;G01N33/86 |
主分类号 |
A61K38/55 |
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