发明名称 MILBEMYCIN OR AVERMECTIN DERIVATIVES
摘要 Novel compounds of formula (I): <CHEM> wherein R<1> is hydrogen or optionally protected hydroxy; R<2> is alkoxy, optionally protected hydroxy, oxo or optionally O-substituted oximino; R<3> is hydrogen, optionally protected hydroxy,or a group 4 min -( alpha -L-oleandrosyl)- alpha -L-oleandrosyloxy or alpha -L-oleandrosyloxy wherein the terminal hydroxy group is optionally protected; R<4>, R<5>, R<6> and R<7> are the same or different and each is hydrogen or an organic radical; and R<8> is an optionally substituted amino or imino group such as optionally O-substituted oxyimino, optionally N-substituted hydrazone, or optionally N-substituted semicarbazone; are useful in the treatment of helminthiasis in humans and animals.
申请公布号 AU5514090(A) 申请公布日期 1990.11.22
申请号 AU19900055140 申请日期 1990.05.17
申请人 BEECHAM GROUP P.L.C. 发明人 GEOFFREY HAROLD BAKER;RODERICK JOHN DORGAN;DAVID OWEN MORGAN;PETER ROBIN SHELLEY;SIMON EDWARD BLANCHFLOWER
分类号 C07H17/08;A01N43/90;A61K31/365;A61K31/70;A61K31/7042;A61K31/7048;A61P33/10;C07D493/22;C07H19/01 主分类号 C07H17/08
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