VERFAHREN ZUM HERSTELLEN EINER IMMUNITAETSGEDAECHTNISZELLSUSPENSION

摘要

The suspension is prepared by (a) separating T cells from cells collected from an immunity sensitized individual immunized against a particular pathogen, (b) mixing the separated cells with an antibody to a histocompatibility antigen specific to a prescribed species of cells to produce Ag-Ab complexes with such cells, (c) adding a blood serum so that complement binder to the complexes and thereby destroys the cells having said antigen, (d) adding to the persisting cells an antibody to a histocompatibility antigen specific to immunity memory cells and (e) separating from the resultant cells the immunity memory cells which have the histocompatibility antigen specific thereto. The cells may be cultured and subcultured successively to establish a continuous line of cells originating in the separated immunity memory cells. They may be useful in the prevention and treatment of infectious diseases or malignant tumours.