发明名称 |
AMINO ACID DERIVATIVES |
摘要 |
The invention relates to new carboxyalkyl dipeptide derivatives of the formula: wherein R is lower alkoxy; R1 is a substituted lower alkyl wherein the substituent is phenyl; R2 and R7 are hydrogen; R3 is lower alkyl; R4 is lower alkyl, R5 is lower alkyl; R4 and R5 may be connected together to form an alkylene bridge of from 2 to 4 carbon atoms; R6 is hydroxy; and the pharmaceutically acceptable salts thereof. These compounds are useful as converting enzyme inhibitors and as antihypertensives. |
申请公布号 |
CA1275349(C) |
申请公布日期 |
1990.10.16 |
申请号 |
CA19860518334 |
申请日期 |
1986.09.16 |
申请人 |
MERCK & CO., INC. |
发明人 |
PATCHETT, ARTHUR A.;HARRIS, ELBERT E.;WYVRATT, MATTHEW J.;TRISTRAM, EDWARD W. |
分类号 |
A61K38/55;A61K31/13;A61K31/19;A61K31/34;A61K31/495;A61K31/535;A61K31/54;A61K38/00;A61K38/05;A61P7/10;A61P9/12;A61P43/00;C07K1/113;C07K5/02;C07K5/06;C07K5/065;C07K14/81 |
主分类号 |
A61K38/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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