发明名称 AMINO ACID DERIVATIVES
摘要 The invention relates to new carboxyalkyl dipeptide derivatives of the formula: wherein R is lower alkoxy; R1 is a substituted lower alkyl wherein the substituent is phenyl; R2 and R7 are hydrogen; R3 is lower alkyl; R4 is lower alkyl, R5 is lower alkyl; R4 and R5 may be connected together to form an alkylene bridge of from 2 to 4 carbon atoms; R6 is hydroxy; and the pharmaceutically acceptable salts thereof. These compounds are useful as converting enzyme inhibitors and as antihypertensives.
申请公布号 CA1275349(C) 申请公布日期 1990.10.16
申请号 CA19860518334 申请日期 1986.09.16
申请人 MERCK & CO., INC. 发明人 PATCHETT, ARTHUR A.;HARRIS, ELBERT E.;WYVRATT, MATTHEW J.;TRISTRAM, EDWARD W.
分类号 A61K38/55;A61K31/13;A61K31/19;A61K31/34;A61K31/495;A61K31/535;A61K31/54;A61K38/00;A61K38/05;A61P7/10;A61P9/12;A61P43/00;C07K1/113;C07K5/02;C07K5/06;C07K5/065;C07K14/81 主分类号 A61K38/55
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