| 摘要 |
Novel pheophoribide derivative of the general formula: <CHEM> (wherein Z is O or NH; n is an integer of 1 to 6; Y is NR min R sec or <CHEM> (wherein R min , R sec and R''' are the same or different and each represents a C1 to C4 lower alkyl group; and X<-> is a halogen or organic acid ion); R1 is an ethenyl group, C1 to C4 lower alkyl group or <CHEM> (wherein m is an integer of 0 to 6, R6 is H or a C1 to C4 lower alkyl group); R2 is CH3, CHO or CH2OH; either of R3 and R4 is H, with the other being OH, or both of them combine to represent =O; R5 is H or CO2CH3) are useful in photodynamic diagnosis and therapy of cancer tissues.
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