摘要 |
PCT No. PCT/CA90/00062 Sec. 371 Date Aug. 21, 1991 Sec. 102(e) Date Aug. 21, 1991 PCT Filed Feb. 23, 1990 PCT Pub. No. WO90/10230 PCT Pub. Date Sep. 7, 1990A polypeptide having immunological activity for use as a diagnostic reagent for the HIV. The polypeptide comprises a substantial portion of each of more than one of the constituent proteins coded for by the HIV-pol gene, namely the amino acid sequences of the reverse transcriptase, RNase H and integrase enzymes coded for by the HIV-pol gene and the amino acid sequences of part of the protease enzyme coded for by the HIV-pol gene, but omitting the active site responsible for proteolytic activity. |