PROCESS FOR PREPARING 1,8-NAPHTHYRIDINES

摘要

1,8-Naphthyridine derivs. of formula (I) are prepd. by reacting a cpd. of formula (II) with a cpd. of formula (III). In the formulas, R1-R3= H or C1-5 alkyl; Q=H or ester or salt forming gp. More specifically (I) is such that Q=H or C1-6 alkyl; R1= H, Me or Et; and R2=R3=H; or R2= Me or Et; and R3= H, Me or Et. (I) have high antibacterial activity against both gram-positive and -negtive bacteria.