The invention refers to a novel method for the preparation of 8-hydroxyoctanoic acid by reaction of 6-chlorohexanol with a dialkyl malonate ester, thermal decarboxylation of the malonic acid derivative and isolation of the 8-hydroxyoctanoic acid as the free acid or as an alkali metal salt.
申请公布号
WO9008125(A3)
申请公布日期
1990.09.20
申请号
WO1990EP00105
申请日期
1990.01.19
申请人
NATTERMANN, A. & CIE. GMBH
发明人
GUENTHER, BERND, RAINER;LOSCH, RAINER;LAUTENSCHLAEGER, HANS;STEINER, KLAUS