PRODUCTION OF L-LYSINE BY FERMENTATION METHOD

摘要

PURPOSE:To obtain L-lysine in remarkably enhanced productivity by culturing a specific L-lysine producing strain in a nutrient medium, producing and accumulating L-lysine in the cultured product and collecting L-lysine from the cultured product. CONSTITUTION:L-Lysine producing strain belonging to the genus Brevibacterium or the genus Corynebacterium and having phenyl alanine analog resistance is cultured in a nutrient medium. Then L-lysine is produced and accumulated in the cultured product and collected from the cultured product. Though bacterium strains of every bacteria belonging to the genus Brevibacterium or the genus Corynebacterium can be used, a bacterium known as L-glutamic acid- producing bacterium of Coryneform such as Brevibacterium devaricatum TCC 14020 or Coryneform fragm ATT 14067 is preferably used.