SUBSTITUED 1,8-NAPHTHYRIDINES, THEIR PREPARATION AND THEIR USE AS ANTIDOTES

摘要

O.Z. 0050/40631 Substituted 1,8-naphthyridines of the general formula I I, where: R1 is mercapto, benzylthio, sulfonyl, amino or NR2R3, where R2 is C1-C12-alkyl, C3-C6-alkenyl, C3-C8-cycloalkyl, substituted or unsubstituted phenyl or phenyl-(C1-C3)-alkyl, or a group -?-A, where A is C1-C8-alkyl, substituted or unsubstituted phenyl, or is amino, alkyl- or dialkylamino where each alkyl radical is of 1 to 6 carbon atoms, phenylamino, morpholino or piperidyl, and R3 is hydrogen, C1-C12-alkyl or C3-C8-cycloalkyl, or R2 and R3 are bonded to one another to form a saturated or unsaturated 5-membered or 6-membered heterocyclic structure which, in addition to the nitrogen atom to which they are bonded, may contain a further heteroatom such as oxygen or nitrogen; hydroxyl, mercapto, halogen or XR4, where X is oxygen or sulfur and R4 is C1-C12-alkyl, C1-C4-alkoxycarbonyl-(C1-C4)-alkyl, C5-C8-cycloalkyl, or substituted or unsubstituted phenyl or phenyl-C1-C3-alkyl, R5 and R7 are each hydrogen, C1-C12-alkyl, C3-C8-cycloalkyl, substituted or unsubstituted phenyl or phenyl-(C1-C3)-alkyl, hydroxyl, halogen, mercapto, C1-C4-alkoxy, C1-C4-alkylthio, amino, mono- or dialkylamino where each alkyl is of 1 to 6 carbon atoms, substituted or unsubstituted phenoxy or phenylthio, halo (Cl-C3)-alkyl, C1-C4-alkoxy-(C1-C3)-alkyl, C1-C4-alkylthio- (C1-C3)-alkyl, amino-(C1-C3)-alkyl, C1-C4-acyloxy, substituted or unsubstituted hydrazino, cyano and thiocyanato, and O.Z. 0050/40631 R5 is hydrogen, C1-C12-alkyl, C3-C8-cycloalkyl, substituted or unsubstituted phenyl or phenyl-(C1-C3)-alkyl, halogen, halo (C1-C3)-alkyl, Cl-C4-alkoxy-(C1-C3)-alkyl, C1-C4-alkylthio- (C1-C3)-alkyl, amino-(C1-C3)-alkyl, carboxyl or C1-C4-alkoxy-carbonyl, their plant-tolerated salts, processes for their manufacture, and their use as safeners.