发明名称 IMPROVING METHOD FOR FIXING IMPLANT
摘要 PURPOSE: To provide a prosthesis material to stimulate a bone to grow inside with a sufficient speed, by providing effective quantity of osteogenesis factor extract(OFE) which is contained in a carrier approved in pharmaceutical sciences and a porous stress supporting material. CONSTITUTION: This prosthesis material is transplanted as a bone exchange material and metal and metal alloy as the stress supporting material include titanium stainless steal, titanium, cobalt, chrome or molybdenum. The, weight ratio of the osteogenesis factor extract(OFE) to the carrier is about 1:5 to 1:100. Furthermore, the carrier approved in the pharmaceutical sciences is ceramics including collagen and this ceramics are hydroxyapatite and tricalcium phosphate, or their mixture. This prosphasis may be composed of a substantially pure osteogenesis active protein, an effective quantity of TGF-β, a carrier approved in the pharmaceutical sciences and a porous stress supporting material.
申请公布号 JPH02218372(A) 申请公布日期 1990.08.31
申请号 JP19890256922 申请日期 1989.09.29
申请人 COLLAGN CORP 发明人 JIYOOJI EICHI CHIYUU;ROSA AAMUSUTORONGU;ROBAATO CHIYAN
分类号 A61L27/00;A61F2/00;A61F2/28;A61L27/22;A61L27/56 主分类号 A61L27/00
代理机构 代理人
主权项
地址