发明名称 POLYSTYRENE POLYMERS AND THEIR USE AS CHOLESTEROL LOWERING AGENTS
摘要 Polymers of structure (I): <CHEM> in which, R<1> is a saturated or unsaturated C6 to C20 alkyl group; R<2> and R<3> are the same or different and are each C1-4alkyl; X<-> is a physiologically acceptable counter ion; a, b and c are numbers which indicate the relative molar percentages of the units present in a random distribution in said polymer, (b) being from about 0.5 to about 10 molar percent, and (c) being from about 30 to about 99 molar percent; and n is a number indicating the number of repeating units in said polymer, processes for their preparation, intermediates useful in their preparation, pharmaceutical compositions containing them and their use in therapy for the lowering of serum cholesterol levels in humans.
申请公布号 ZA8809521(B) 申请公布日期 1990.08.29
申请号 ZA19880009521 申请日期 1988.12.21
申请人 SMITH KLINE & FRENCH LABORATORIES LIMITED 发明人 ALBERT ANDRZEJ JAXA-CHAIMEC;DEIDRE MARY BERNADETTE HICKEY
分类号 A61K31/785;A61P3/06;A61P39/02;C08F8/44;C08F12/28;C08F212/00 主分类号 A61K31/785
代理机构 代理人
主权项
地址