发明名称 Nitroso-N-( beta -chloro ethyl)-carbamoyl peptides
摘要 The invention relates to new peptide derivatives of the general Formula I <IMAGE> (I) wherein R is a group derived from any oligopeptide by removing a terminal amino group, or-if the oligopeptide comprises a diamino carboxylic acid-the amino group in the omega -position, or the terminal and omega -amino groups; and stands for the integral number 1 or 2 and acid addition slats thereof and a process for the preparation thereof. The new compounds of the general Formula I exhibit antitumor activity.
申请公布号 US4950651(A) 申请公布日期 1990.08.21
申请号 US19850725146 申请日期 1985.04.19
申请人 CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. 发明人 SULI, HELGA;MEDZIHRADSZKY, KALMAN;MEDZIHRADSZKY NEE SCHWEIGER, HEDVIG;LAPIS, KAROLY;KOPPER, LASZLO;JENEY, ANDRAS
分类号 A61K31/17;A61K38/00;A61K38/07;A61P35/00;A61P35/02;C07C67/00;C07C239/00;C07C275/68;C07K5/078;C07K5/09;C07K5/103;C07K5/117;C07K14/595;C07K14/685;C07K14/695 主分类号 A61K31/17
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