发明名称 |
Nitroso-N-( beta -chloro ethyl)-carbamoyl peptides |
摘要 |
The invention relates to new peptide derivatives of the general Formula I <IMAGE> (I) wherein R is a group derived from any oligopeptide by removing a terminal amino group, or-if the oligopeptide comprises a diamino carboxylic acid-the amino group in the omega -position, or the terminal and omega -amino groups; and stands for the integral number 1 or 2 and acid addition slats thereof and a process for the preparation thereof. The new compounds of the general Formula I exhibit antitumor activity.
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申请公布号 |
US4950651(A) |
申请公布日期 |
1990.08.21 |
申请号 |
US19850725146 |
申请日期 |
1985.04.19 |
申请人 |
CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. |
发明人 |
SULI, HELGA;MEDZIHRADSZKY, KALMAN;MEDZIHRADSZKY NEE SCHWEIGER, HEDVIG;LAPIS, KAROLY;KOPPER, LASZLO;JENEY, ANDRAS |
分类号 |
A61K31/17;A61K38/00;A61K38/07;A61P35/00;A61P35/02;C07C67/00;C07C239/00;C07C275/68;C07K5/078;C07K5/09;C07K5/103;C07K5/117;C07K14/595;C07K14/685;C07K14/695 |
主分类号 |
A61K31/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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