发明名称 ISOMERIC DIDEOXYNUCLEOSIDES
摘要 KAN 4430/35 Compounds of the formula wherein A is 6-Amino-9H-purin-9-yl or 2-Amino-6-hydroxy-9H-purin-9-yl, wherein the amino group may be replaced by NHC(O)R and N=CHR3R4, and R is OH or OC(O)R1, wherein R1, R2, R3 and R4 is each independently straight or branched chain C1-20 alkyl, C1-l2 alkoxyalkyl, substituted or unsubstituted phenoxy-C1-4-alkyl, substituted or unsubstituted phenyl with the substituents selected from the group consisting of halogen, C1-4 alkoxy, nitro, hydroxy, carboxyl or alkylamino, and pharmaceutically acceptable salts thereof, are useful in the treatment of retroviral infections.
申请公布号 CA2009658(A1) 申请公布日期 1990.08.13
申请号 CA19902009658 申请日期 1990.02.09
申请人 HOFFMANN-LA ROCHE (F.) AG 发明人 HURYN, DONNA M.;TAM, STEVE Y.;WEIGELE, MANFRED
分类号 C07H19/16;A61K31/52;A61K31/522;A61P31/12;C07D307/20;C07D307/22;C07D339/08;C07D405/04;C07D409/04;C07D473/00;C07D473/18;C07D473/34;C07H9/02;C07H13/00;C07H13/12;C07H15/26;C12P19/40;(IPC1-7):C07D473/34;A61K31/70 主分类号 C07H19/16
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