发明名称 DIPEPTIDE DERIVATIVE HAVING ENZYME INHIBITING ACTION
摘要 Compounds of the formula I <IMAGE> in which R<1> is (subst.) heterocyclyl-alkyl, -alkoxy, -cycloalkyl, -cycloalkoxy and the corresponding heterocyclylmercapto compounds, A and B are, independently of one another, an amino acid, R<2> is hydrogen, alkyl, cycloalkyl, cycloalkyl-alkyl, aryl or aryl-alkyl, R<3> is hydrogen, alkyl, aryl, aryl-alkyl or hydroxyl, and R<4> is a radical (CH2)0-4CHR<5>-D, with R<5> = hydrogen, alkyl, alkoxy, alkylthio, alkylamino, hydroxyl, azido or halogen and D = (subst.) heterocyclyl, have enzyme-inhibiting properties. Processes for preparing compounds of the formula I and the use thereof for treating high blood pressure and viral diseases are described.
申请公布号 JPH02202899(A) 申请公布日期 1990.08.10
申请号 JP19890317941 申请日期 1989.12.08
申请人 HOECHST AG 发明人 BUORUFUUURURITSUHI NIKERU;HANSUIERUKU URUBATSUHA;DEIITAA RUPERUTO;BERUNBUARUTO SHIERUKENSU
分类号 C12N9/99;A61K38/00;A61K38/05;A61K38/55;A61P9/12;A61P31/12;C07D277/42;C07K1/02;C07K1/113;C07K5/02;C07K5/06;C07K5/065;C07K14/81 主分类号 C12N9/99
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