EXPRESSION OF RECOMBINANT FIBRONECTIN IN GENETICALLY ENGINEERED CELLS

摘要

A method of producing homogeneous cellular fibronectin of mammalian origin, which is a homodimer, as well as recombinant cellular fibronectin. They can be produced having all or a portion of regions B, A, V or combinations of these. Specifically, homodimers and heterodimers can be produced having the carboxy terminal 25 amino acids of region V deleted. The recombinant cellular fibronectin is useful in any application in which naturally-occurring fibronectin can be used.