摘要 |
<p>The present invention describes a process to obtain 4-substituted 2-alkoxytetrahydrofuran derivatives of formula I. <CHEM> wherein, -R1 represents an alkyl or phenylalkyl radical; -R2 is hydrogen, C1-C4-acyl or C1-C4-alkoxycarbonyl; -R3 is either an electron pair, in which case t means nothing and q is zero, or R3 is hydrogen or C1-C4-alkyl, in which case t is (+) and q=1;.A<-> is a pharmaceutically acceptable anion. These compounds are antagonists of PAF and, therefore, useful for the treatment of the diseases in which this substance is involved</p> |