发明名称 |
COMBINATION OF SQUALENE SYNTHETASE INHIBITOR AND OTHER TYPE OF SERUM CHOLESTEROL REDUCING AGENT AND METHOD FOR LOWERING SERUM CHOLESTEROL USING SUCH COMBINATION |
摘要 |
HX24 COMBINATION OF A SQUALENE SYNTHETASE INHIBITOR AND OTHER TYPE OF SERUM CHOLESTEROL REDUCING AGENT AND METHOD FOR LOWERING SERUM CHOLESTEROL USING SUCH COMBINATION A pharmaceutical combination is provided which includes an inhibitor of the enzyme squalene synthetase and a pharmaceutical which reduces serum cholesterol by a mechanism other than inhibiting production of the enzyme HMG CoA reductase or the enzyme squalene synthetase, namely, an antihyperlipoproteinemic agent or antihyperlipemic agent, for example, probucol or gemfibrozil. A method for reducing serum cholesterol or inhibiting formation of or treating atherosclerosis using the above combination is also provided.
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申请公布号 |
CA2007641(A1) |
申请公布日期 |
1990.08.01 |
申请号 |
CA19902007641 |
申请日期 |
1990.01.12 |
申请人 |
KARANEWSKY, DONALD S.;BILLER, SCOTT A.;GORDON, ERIC M.;SCOTT, WILLIAM A. |
发明人 |
KARANEWSKY, DONALD S.;BILLER, SCOTT A.;GORDON, ERIC M.;SCOTT, WILLIAM A. |
分类号 |
A61K31/10;A61K31/215;A61K31/455;A61K31/56;A61K31/60;A61K31/66;A61K31/715;A61K31/785;A61K45/00;A61P3/06;(IPC1-7):A61K31/00 |
主分类号 |
A61K31/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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