发明名称 PROCESS FOR PREPARING PYRIMIDINE-THIO ALKYL PYRIDINE DERIVATIVES
摘要 2-Pyrimidylthiomethyl-pyridine derivs. of formula (I) and their therapeutically tolerable acid addition salts are prepd. by reacting a cpd. of formula (II) with a cpd. of formula (III). In the formulas, R1-R4 each = H, lower alkyl, halogen, amino or OH; R5 = free electron pair or lower alkyl; X = halogen when R5 is lower alkyl; m = 0 or 1. (I) have bronchosecretolytic, mucolytic and antiinflammatory activity, and are active after oral or parenteral administriation.
申请公布号 KR900005110(B1) 申请公布日期 1990.07.19
申请号 KR19840002350 申请日期 1984.05.01
申请人 LUDWIG HEUMANN & CO. GMBH. 发明人 SCHICKANEDER HELMUT;ENGLER HEIDRUN;SZELENY ISTVAN;AHRENS KURTHENNING
分类号 A61K31/505;A61P11/10;A61P29/00;C07D401/12;(IPC1-7):C07D401/12 主分类号 A61K31/505
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