发明名称 |
BMY-28121, a new antitumor antibiotic |
摘要 |
A new antitumor antibiotic designated herein as BMY-28121 is produced by fermentation of Streptomyces albus strain K7331-113 (ATCC 39897). BMY-28121, which may be recovered from the fermentation broth in either its natural free hydroxy form (BMY-28121A) or methyl ether form (BMY-28121B), inhibits gram-positive bacteria and anaerobes and inhibits the growth of mammalian tumors such as P-388 leukemia, L-1210 leukemia and B16 melanoma.
|
申请公布号 |
US4935362(A) |
申请公布日期 |
1990.06.19 |
申请号 |
US19870031955 |
申请日期 |
1987.03.30 |
申请人 |
BRISTOL-MYERS COMPANY |
发明人 |
TSUNAKAWA, MITSUAKI;KONISHI, MASATAKA;MIYAKI, TAKEO |
分类号 |
C07D487/04;C12P17/18 |
主分类号 |
C07D487/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|