发明名称 |
TERTIAERE HYDROXYALKYLXANTHINE, VERFAHREN ZU IHRER HERSTELLUNG, DIE SIE ENTHALTENDEN ARZNEIMITTEL UND IHRE VERWENDUNG. |
摘要 |
PCT No. PCT/EP86/00401 Sec. 371 Date Mar. 16, 1987 Sec. 102(e) Date Mar. 16, 1987 PCT Filed Jul. 8, 1986 PCT Pub. No. WO87/00523 PCT Pub. Date Jan. 29, 1987.Tertiary hydroxyalkylxanthines having the general formula (I), characterized by the fact that at least one of the residues R1 and R3 represents a tertiary hydroxyalkyl group of formula (Ia) in which R4 represents an alkyl group having up to 3 carbon atoms and n a whole number from 2 to 5; the other residue which may remain R1 or R3 is a hydrogen atom or an aliphatic hydrocarbon residue R5 having up to 6 carbon atoms, in which the carbon chain may be separated by a maximum of two oxygen atoms or be substituted by an oxo group or two hydroxy groups at the most, and R2 represents an alkyl group with 1 to 4 carbon atoms. Also described is a process for manufacturing these compounds, which are suitable for the manufacture of medicines, in particular for use in the prevention and/or treatment of peripheral and/or cerebral irrigation disorders. <IMAGE> (I) <IMAGE> (Ia) |
申请公布号 |
AT53211(T) |
申请公布日期 |
1990.06.15 |
申请号 |
AT19860904158T |
申请日期 |
1986.07.08 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
GEBERT, ULRICH;OKYAYUZ-BAKLOUTI, ISMAHAN;THORWART, WERNER |
分类号 |
C07D473/00;A61K31/52;A61K31/522;A61P3/00;A61P9/00;A61P9/08;A61P25/28;C07D473/04;C07D473/06;C07D473/08 |
主分类号 |
C07D473/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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