摘要 |
Compounds of the general formulae: (I) (I') wherein R1 and R2, which can be the same or different, are hydrogen atoms or C1-C5-alkyl radicals, C3-C5-alkenyl radicals or phenyl radicals or, together with the carbon atom to which they are attached, form a saturated or unsaturated C3-C7 ring, R3 and R4, which can be the same or different, are hydrogen atoms, straight-chained or branched C1-C10-alkyl radicals, straight-chained or branched C3-C7-alkenyl radicals, C3-C7-cycloalkyl radicals, C3-C7-cycloalkenyl radicals, phenyl, arylalkyl or hetarylalkyl radicals, R5 is a hydrogen atom or a lower alkyl radical and X is an oxygen or sulphur atom or an imino group, display an immunosuppressive action, and more especially a specifically effective immunosuppressive action thereby having a significant advantage over prior non-specific immunosuppressives.
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申请人 |
BOEHRINGER MANNHEIM G.M.B.H. |
发明人 |
TSAKLAKIDIS, CHRISTOS;BOSIES, ELMAR;SCHULTZ, MICHAEL;HAAG, RAINER;HERRMANN, DIETER;PAHLKE, WULF |