发明名称 |
ANTISENSE OLIGONUCLEOTIDES TO C-MYB PROTO-ONCOGENE AND USES THEREOF |
摘要 |
Oligonucleotides are provided having a nucleotide sequence complementary to at least a portion of the mRNA transcript of the human c-myb gene. These "antisense" oligonucleotides are hybridizable to the c-myb mRNA transcript. Such oligonucleotides are useful in treating hematologic neoplasms and in inducing immunosuppression. They are particularly useful as bone marrow purging agents. |
申请公布号 |
AU5035090(A) |
申请公布日期 |
1990.06.12 |
申请号 |
AU19900050350 |
申请日期 |
1989.11.03 |
申请人 |
TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCAT |
发明人 |
ALAN M. GEWIRTZ;BRUNO CALABRETTA |
分类号 |
C07K14/82;C12N15/113 |
主分类号 |
C07K14/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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