FUNCTIONAL CHIMERA ANTIBODY

摘要

The present invention discloses novel biologically produced bifunctional chimeric antibodies, directed against human carcinoembryonic antigen and metal chelates, having two sets of antigen-specific variable regions of defined amino acid sequences. DNA constructs for the light and heavy chain variable regions comprising the novel antibodies of the invention are disclosed. Eukaryotic host cells capable of biological expression of the bifunctional chimeric antibodies and comprising the novel bifunctional chimeric antibody-encoding DNA constructs are also provided.