Absorbable calcitonin medicament.

摘要

Calcitonin is a polypeptide hormone having various medical activities used for treatment of osteoporosis, hypercalcemia, Paget's disease etc. There is provided an intranasal medicament composition comprising [a] calcitonin and [b] at least one absorption enhancer selected from benzyl alcohol, ethanol, and polyethylene glycol 400 [Macrogol 400]. There is also provided means enabling application of the composition to the nasal mucosa. By the use of a specific absorption enhancer in the calcitonin internasal composition, efficiency of absorbing across the membrane of the nasal cavity is improved.