ADAPTIVE FILTER CONCENTRATE FLOW CONTROL SYSTEM AND METHOD

摘要

An adaptive filter concentrate flow control system includes a filter system, a pumping system driving feed fluid, concentrate and filtrate flowing through the filter system and a flow control system controlling the pumping system to maintain optimum filtrate flow rates along a control curve in a transmembrane pressure--feed fluid rate--filtrate flow rate three dimensional space. Actual sensed operating point data is used to locate the control curve so as to assure an optimized filtrate flow rate at which reversible blocking of the membrane has begun to occur without irreversible plugging. The system is advantageously employed to control and maximize the flow of plasma in a plasmapheresis system.