| 摘要 |
1-Oxa-1-dethia-cephalosporin cpds. of formula (I), their hydrates, salts and esters are prepared. In (1), R1 is (a) [R5= methyl, ethyl, carboxymethyl or 2-carboxyisopropyl ; R2 and R3 are each H or methyl; R4 is H, methyl, carboxy, trifluoromethyl or monofluoromethyl. (I) are useful as broad spectrum antibacterials and also effectve against beta-lactamase producing pseudomonas strains.
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