发明名称 Dibenzocycloheptene derivatives, process for their preparation and their use as medicaments.
摘要 <p>The invention relates to the compounds of formula (I), &lt;IMAGE&gt; in which: - X denotes a nitro group or an R2R3N- group in which R2 and R3 which are identical or different denote a hydrogen atom, an alkyl, alkenyl or alkynyl radical, or an R4CO-, -COOR5 or R6R7NCO- radical, R4, R5, R6 and R7 denote alkyl radical, without R2 and R3 being both capable of denoting an alkyl radical, - either both Y and Z denote a hydrogen atom - or together with the carbon atom to which they are bonded they form a carbonyl group and - R1 denotes a hydrogen atom, an alkyl, alkenyl or alkynyl radical or a -COOR8 radical in which R8 denotes an alkyl radical. The compounds of formula (I) exhibit advantageous pharmacological properties which justify their use as medicaments.</p>
申请公布号 EP0368756(A1) 申请公布日期 1990.05.16
申请号 EP19890403081 申请日期 1989.11.08
申请人 ROUSSEL-UCLAF 发明人 FRECHET, DANIEL;HUNT, PETER FRANCIS;NEDELEC, LUCIEN;OBERLANDER, CLAUDE
分类号 C07D451/00;A61K31/46;A61P25/28;C07D451/02 主分类号 C07D451/00
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