发明名称 Target-specific cytotoxic liposomes
摘要 The A fragment of the diphtheria toxin (DTA) was encapsulated in pH-sensitive liposomes. This novel reagent is extremely cytotoxic to cells expressing surface antigen which is recognized by the immunoliposome. The reagent is not toxic to cells which do not express the antigen. Thus, this reagent, or others similarly prepared represent potential anticancer reagents.
申请公布号 US4925661(A) 申请公布日期 1990.05.15
申请号 US19870012240 申请日期 1987.02.09
申请人 HUANG, LEAF 发明人 HUANG, LEAF
分类号 A61K9/127;C12N15/88 主分类号 A61K9/127
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