发明名称 PROSTAGLANDIN-DERIVATIVES HAVING ANTITHROMBOTIC ACTIVITY
摘要 The compounds of formula (I), wherein: n = 2, 3; m = 4, 5, 6, 7; X = NHR, CH2NHR, NHNH2; R = H, a linear or branched (C1-C4)alkyl, a linear or branched (C1-C4)acyl; Y = CH2NH2, COOH, CONH2 (with the exclusion of the compounds wherein n = 2, m = 5, X = NHR with R = H, a linear or branched (C1-C4)alkyl, a linear or branched (C1-C4)acyl; Y = COOH, CONH2) including all optical and/or geometrical isomers, alone or in admixture, and their salts, which inhibit the platelet aggregation in the blood and which can be prepared for use as antiplatelet, antithrombotic agents.
申请公布号 WO9003170(A2) 申请公布日期 1990.04.05
申请号 WO1989IT00061 申请日期 1989.09.12
申请人 IBI ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZIN 发明人 VALCAVI, UMBERTO
分类号 A61K31/557;A61P7/02;C07C69/716;C07C69/738;C07C211/03;C07C211/21;C07C229/28;C07C229/46;C07C233/05;C07C237/06;C07C237/22 主分类号 A61K31/557
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