| 摘要 |
<p>Target cells bearing a distinguishing surface antigen may be killed selectively, without harm to bystander cells, by administering myeloperoxidase, eosinophil peroxidase, thyroperoxidase, or salivary peroxidase, conjugated to a binding agent capable of specifically binding said surface antigen, and a hydrogen peroxide-producing enzyme conjugated to a second binding agent. The hydrogen peroxide-producing enzyme, in the presence of its substrate, generates hydrogen peroxide, which is utilized by the peroxidase to lethally halogenate the target cells.</p> |
