发明名称 |
SUBSTITUTED 3,4-DIAMINO-1,2,5-THIADIAZOLES HAVING HISTAMINE H2-RECEPTOR ANTAGONIST ACTIVITY |
摘要 |
<p>Histamine H2-receptor antagonists of the formula I wherein A, m, z, n and R1 are as defined herein, and their nontoxic pharmaceutically acceptable salts are novel anti-ulcer agents which are prepared by ring closure of a substituted ethanediimidamide of the formula II</p> |
申请公布号 |
CA1267412(A) |
申请公布日期 |
1990.04.03 |
申请号 |
CA19850483419 |
申请日期 |
1985.06.07 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
ALGIERI, ALDO A.;CRENSHAW, RONNIE R. |
分类号 |
C07D239/47;A61K31/425;A61K31/426;A61K31/433;A61K31/496;A61K31/505;A61P1/04;A61P43/00;C07D233/64;C07D239/42;C07D263/48;C07D277/20;C07D277/48;C07D283/00;C07D285/10;C07D417/12;C07D417/14;(IPC1-7):C07D417/00;A61K31/395 |
主分类号 |
C07D239/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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