| 摘要 |
A merocyanine dye having the formula: <IMAGE> wherein: R1 and R2 independently are H, alkyl, alkoxy or aryl; R7 and R8 are H or any of R1 and R2, R1 and R7, and R2 and R8 can together comprise the atoms necessary to form a fused aromatic ring on the benzene radical to which they are attached and with the stipulation that only one of R1 and R2 can be H; R5 and R6 comprise alkyl of from 1-18 carbon atoms, provided that the sum of the carbon atoms in R5 and R6 together is at least 8; R9 is an alkylene group of 2-9 nuclear carbon and hetero atoms; and Z+ is a cation. This dye is useful in a method for inactivating viruses comprising contacting the viruses with the compound and exposing the resulting mixture to visible light to excite and inactivate the viruses. The compounds are also useful in the irradiation-induced inactivation of leukemia cells.
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