发明名称 |
Antidiabetic phosphates. |
摘要 |
<p>Phosphates are disclosed which stimulate the enzyme fructose-1,6-bisphosphatase and inhibit the enzyme 6-phosphofructo-1-kinase, thereby lowering glucose levels in mammals. These phosphates may thus be used to treat hyperglycemia and/or diabetes. Processes for the synthesis of the phosphates are also disclosed.</p> |
申请公布号 |
EP0354323(A2) |
申请公布日期 |
1990.02.14 |
申请号 |
EP19890110990 |
申请日期 |
1989.06.16 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
DEVRIES, VERN GORDON;CLAUS, THOMAS HARRISON;FLOYD JR , MIDDLETON BRAWNER;AYRAL-KALOUSTIAN, SEMIRAMIS |
分类号 |
C07D307/20;A01G7/06;A61K31/665;A61P3/08;A61P3/10;A61P43/00;C07F9/655;C07H11/04;C07J51/00;C12N9/99 |
主分类号 |
C07D307/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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