发明名称 |
THE USE OF IMEXON AS AN IMMUNE SUPPRESSIVE AND PHARMACEUTICALCOMPOSITIONS CONTAINING IMEXON |
摘要 |
The present invention relates to the use of 4-imino-1,3-diazabicyclo[3.1.0]hexan-2-one (imexon) as an immunosuppressive agent. Imexon selectively suppresses beta -lymphocyte activation and can be employed for the treatment of B-cell or plasma-cell leukaemia and neoplasms. Imexon is used in the treatment of those disorders in which polyclonal B-cell proliferation is of pathophysiological, symptomatic or clinical relevance such as, for example, for autoimmune diseases. |
申请公布号 |
AU3887789(A) |
申请公布日期 |
1990.02.01 |
申请号 |
AU19890038877 |
申请日期 |
1989.07.24 |
申请人 |
BOEHRINGER MANNHEIM G.M.B.H. |
发明人 |
DIETER HERRMANN;RAINER HAAG;ELMAR BOSIES;UWE BICKER;WOLFGANG KAMPE |
分类号 |
A61K31/395;A61K31/505;A61P31/12;A61P37/06 |
主分类号 |
A61K31/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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