| 发明名称 |
N-[[5-(TRIFLUOROMETHYL)-6-METHOXY-1- NAPHTHALENYL]-THIOXOMETHYL AND CARBONYL]-N- METHYLGLYCINAMIDES |
| 摘要 |
<p>Disclosed herein are tolrestat and oxotolrestat amides and methods of preparation. The amides are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.</p> |
| 申请公布号 |
CA1264471(A) |
申请公布日期 |
1990.01.16 |
| 申请号 |
CA19860511236 |
申请日期 |
1986.06.10 |
| 申请人 |
AMERICAN HOME PRODUCTS CORPORATION |
发明人 |
SESTANJ, KAZIMIR;FERDINANDI, ECKHARDT S.;KRAML, MICHAEL;BELLINI, FRANCESCO |
| 分类号 |
A61K31/165;A61K31/17;A61K31/27;A61K31/70;A61K31/7024;A61P3/08;A61P3/10;A61P13/02;A61P15/00;A61P25/00;A61P27/02;A61P27/12;C07C67/00;C07C231/00;C07C235/66;C07C237/22;C07C239/00;C07C271/20;C07C275/14;C07C275/50;C07C275/70;C07C325/00;C07C327/48;C07H13/04;(IPC1-7):A61K31/70;C07C127/22;C07C103/82;C07C153/063 |
主分类号 |
A61K31/165 |
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