发明名称 |
RADIOHALOGENATED COMPOUNDS FOR SITE SPECIFIC LABELING |
摘要 |
Radiohalogenated compounds which are useful as intermediates for preparing radiohalogenated antibody conjugates in which the radiohalogenated compound is site specifically attached to an oxidized carbohydrate moiety of an antibody or antibody fragment are disclosed. Methods for making the compounds and the antibody conjugates as well as methods of use of the same are also disclosed. |
申请公布号 |
AU3772889(A) |
申请公布日期 |
1990.01.05 |
申请号 |
AU19890037728 |
申请日期 |
1989.06.06 |
申请人 |
CYTOGEN CORPORATION |
发明人 |
DANIEL J. COUGHLIN;BENJAMIN A. BELINKA;VERNON L. ALVAREZ |
分类号 |
A61K39/395;A61K51/00;A61K51/10;A61P31/04;A61P31/12;A61P35/00;C07B59/00;C07C215/76;C07C217/84;C07C243/22;C07C243/38;C07K1/113;C07K14/00;C07K14/705;C07K16/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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