Method and device for attachement of biologically useful materials to a solid phase.

摘要

A method and kit for indirectly attaching a biologically useful material to a solid phase by means of a linking polymer is described. The linking polymer is selected from difunctional polyalkylene ether polymers wherein the difunctionality is at the distal and proximal ends of the polymer. The proximal end of the polymer is attached to the solid phase and the distal end of the polymer is joined to the material. Very low density of the linking polymer (less than 100 nanomoles per square meter) reduces interference with and increases the activity of the material. Enzymes and other active molecules or combinations of molecules are immobilized in the solid phase.