The invention relates to liposomes coupled to a hormone e.g. a cytokine in which the hormone retains specific binding activity to its cell membrane receptor and to a process for making them. The liposomes of the invention may be used as delivery vehicles for targeted delivery of a diagnostic or pharmaceutically active substance.
申请公布号
WO8911270(A1)
申请公布日期
1989.11.30
申请号
WO1989EP00521
申请日期
1989.05.12
申请人
SANDOZ AG;VESTAR, INC.
发明人
KONIGSBERG, PAULA, JEAN;RICHER, LEROY, LEONARD;SCHMIDT, PAUL, GARDNER;ULIANA, JOSEPH, ANTHONY