摘要 |
<p>New and useful compounds which possess outstanding antitumor activity in mice and cell cultures and are active against schistosomiasis these compounds having structural formula (I), wherein R is selected from H, lower alkoxy, OH and phenoxy; R' is selected from H and CH3; R'' is selected from CH3 and CR1HOOCNHR2; R''' is selected from H and CR1HOOCNHR2; R', R'', and R''' are different from each other; when R' is CH3, R is other than H; R1 is selected from H and lower alkyl; and R2 is selected from lower alkyl, aminoalkyl and phenyl; and their pharmaceutically acceptable salts.</p> |