| 摘要 |
PURPOSE:To obtain a remedy for cornea capable of curing the wound of anterior epithelium of the cornea by the application to the cornea and correcting the visual acuity by the use of the remedy as a buffering agent for a contact lens by bonding fibronectin to a solid containing polymeric hyaluronic acid. CONSTITUTION:A remedy for cornea is produced by bonding fibronectin to a corneal protection agent composed of a solid containing polymeric hyaluronic acid. Fibronectin has a function to bond with a fibrous protein such as collagen. Since collagen is the main component of cornea, the above remedy for cornea is effective in remedying prolonged defect of the anterior epithelium of the cornea. The period of treatment can be shortened compared with other drug free from fibronectin. The visual acuity can be improved since a contact lens can be used during the treatment period. The fibronectin is separated from the solid according to the dissolution of the hyaluronic acid and is dissipated after remaining to the surroundings to prolong the active period of the drug. |
