发明名称 |
PHOSPHORAMIDITE REAGENT FOR CHEMICAL SYNTHESIS OF MODIFIED DNA |
摘要 |
5,6-dihydro-5-azacytidine phosphoramidite is useful in the synthesis of oligonucleotides and DNA containing dihydro-5-aza- and 5-azacytosine bases. The modified oligonucleotides which contain 5-azacytosine residues at specific sites can be used to determine the mechanism of selective gene activation and the relationship existing between the presence of the triazine base and inhibition of DNA methylation. |
申请公布号 |
AU3368189(A) |
申请公布日期 |
1989.11.03 |
申请号 |
AU19890033681 |
申请日期 |
1989.04.06 |
申请人 |
UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED |
发明人 |
VICTOR E. MARQUEZ;AMANDA J. GODDARD |
分类号 |
C07H1/02;C07H19/04;C07H19/12;C07H19/23;C07H21/00;C07H21/04 |
主分类号 |
C07H1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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