摘要 |
<p>Hydantoin derivatives of formula (I), wherein Ra and Rb are same or different, each being hydrogen atom, alkanoyl, substituted or non-substituted aroyl, heteroaroyl, alkoxycarbonyl, substituted or non-substituted aralkoxycarbonyl, aryloxycarbonyl, N-alkylcarbomoyl, N,N-dialkylcarbamoyl, substituted or non-substituted N-aralkylcarbamoyl, alkoxyalkyl, 1-(acyloxy)alkyl, alkylmercapto, substituted or non-substituted arylmercapto, alkylsulfinyl, substituted or non-substituted arylsulfinyl, alkylsulfonyl or substituted or non-substituted arylsulfonyl, but both of Ra and Rb do not concurrently mean hydrogen atom, a process for the preparation of the derivatives, and use thereof as an agent for preventing and curing chronic complications due to diabetes.</p> |