发明名称 |
7-(2-METHYL-4-AMINOPYRROLIDINYL)NAPHTHYRIDINE AND QUINOLINE COMPOUNDS |
摘要 |
<p>Naphthyridine and quinoline compounds having the formula: <CHEM> wherein A is CH or N; Z is an amine having the formula: <CHEM> R is o,p-difluorophenyl or p-fluorophenyl; and R1 is hydrogen or a carboxy protecting group. The compounds of the invention have antibacterial activity and improved solubility and pharmacokinetic properties.</p> |
申请公布号 |
EP0302371(A3) |
申请公布日期 |
1989.10.18 |
申请号 |
EP19880112103 |
申请日期 |
1988.07.27 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
ROSEN, TERRY J.;CHU, DANIEL T. |
分类号 |
A61K31/435;A61K31/47;A61P35/00;C07D401/04;C07D471/04;(IPC1-7):C07D401/04 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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