WATER SOLUBLE IBUPROFEN COMPOSITIONS AND METHODS OF MAKING THEM

摘要

A novel water soluble alkali metal salt of ibuprofen is prepared by reacting ibuprofen and an alkali metal bicarbonate in a aqueous medium. The salt is useful in treating pain, inflammation, and fever in mammals. It permits the preparation of a number of novel formulations which result in pharmaceutically and commercially acceptable dosage forms.