发明名称 |
Methods and compositions for immunologically modulating growth hormone receptor activity |
摘要 |
The activity of growth-associated receptors is modulated in vivo in a controlled and reproducible fashion by immunizing animals against target growth-associated receptors. This is accomplished by the use of immunogens predetermined to induce primarily agonist or antagonist responses. The immunogens include anti-ligand antibodies and receptor derivatives.
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申请公布号 |
US4857637(A) |
申请公布日期 |
1989.08.15 |
申请号 |
US19870061942 |
申请日期 |
1987.06.12 |
申请人 |
GENENTECH, INC. |
发明人 |
HAMMONDS, R. GLENN;LEUNG, DAVID W.;MARTIN, JR., DAVID W.;SPENCER, STEVEN A.;WOOD, WILLIAM I. |
分类号 |
A61K39/00;C07K14/71;C07K16/26;C07K16/28;C12N15/38 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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