发明名称 Methods and compositions for inhibiting lipoxygenase
摘要 This invention encompasses a pharmaceutical composition comprising a pharmaceutical carrier and an effective lipoxygenase inhibiting amount of a compound of the formula: <IMAGE> wherein: R1 and R2 are same or different members of the group consisting of 1,1-dimethyl ethyl, halo, phenyl and substituted phenyl; Alk is straight or branched chain lower alkylene; R4 is hydrogen or lower alkyl; R3 is hydrogen or lower alkyl; or a cycloalkyl group of from 3 to 8 carbon atoms. The formulation of this invention are useful as anti-inflammatory and anti-allergy agents.
申请公布号 US4857558(A) 申请公布日期 1989.08.15
申请号 US19880196927 申请日期 1988.05.20
申请人 G. D. SEARLE & CO. 发明人 MUELLER, RICHARD A.
分类号 C12N9/99;A61K31/10;A61K31/12;A61P11/00;A61P17/00;A61P27/16;A61P29/00;A61P37/08;A61P43/00;C07C67/00;C07C313/00;C07C321/26;C07C323/20;C07C323/22;C07C323/23 主分类号 C12N9/99
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