发明名称 Synthetic resin matrix system incorporating healing enhancer
摘要 An apparatus and method is described for applying epidermal growth factor (EGF) for achieving healing enhancement at a wound site. The human source of epidermal growth factor, designated as hEGF, is applied from the synthetic resin matrix system of this invention, and which comprises a polymer, such as poly(2-hydroxyl ethyl methyl methacrylate), referred to as PHEMA, an organic solvent, such as polyethylene glycol (PEG), and a hydrogen binding plasticizer, such as dimethylsulfoxide (DMSO). The plasticizer regulates the set-up time of the synthetic resin, so that the more plasticizer present, the shorter the set-up time. The dressing, once formed, and having the healing enhancer contained therein, may be sealed within various backing sheets, in order to preserve its aseptic condition. When ready for use, one of the backing sheets may be peeled away to expose the resin pad with the emobodied healing enhancer, ready for application to the wound site.
申请公布号 US4857334(A) 申请公布日期 1989.08.15
申请号 US19880199375 申请日期 1988.05.27
申请人 ENQUAY PHARMACEUTICAL ASSOCIATES 发明人 KOROL, BERNARD;NATHAN, PAUL
分类号 A61K9/22;A61L15/24;A61L15/44;A61L26/00 主分类号 A61K9/22
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