| 摘要 |
Cpds. (I):- (where R and R1 are H or 1-7C alkyl; R2 is H or 1-7C alkyl or COOR6; R6 is 1-7C alkyl; B is or or provided R2 is COOR6, R3 is H or halogen; R4 = OH, aryl SO2, aryl SO3, (1-7C alkyl) SO2, (1-7C alkyl) SO3, (1-6C alkyl) CO or (1-6C alkyl) COO; R5 is H or R4+R5 is a supplementary C-N bond) are prepd. by hydrolysis of the corresponding 7-ketal opt. followed by oxidn. of the N-oxide, or reduction of the N-oxide to the free base or the N-hydroxy deriv., or photolysis of the N-oxide to the epoxide or by reduction of the tetrahydro-deriv. of by introduction of R4 (other than OH) thence by formation of the 3,4-double bond, or by cyclisation of a substd. acetanilide. |
