发明名称 Spiro-hydantoins as aldose reductase inhibitors
摘要 The invention relates to spirohydantoins of the formula I <IMAGE> (I) where R1 and R2 are defined hereinbelow. Also disclosed are methods of preparation, pharmaceutical compositions containing at least one of these compounds, and methods of using said compounds for treatment and prevention of complications of diabetes and galactosemia.
申请公布号 US4853401(A) 申请公布日期 1989.08.01
申请号 US19870033427 申请日期 1987.04.01
申请人 G. D. SEARLE & CO. 发明人 BOVY, PHILIPPE R.;GILLET, CLAUDE;LENAERS, ALBERT;NIEBES, PAUL;ROBA, JOSEPH;LAMBELIN, GEORGES
分类号 C07D235/02 主分类号 C07D235/02
代理机构 代理人
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